Chlorella was discovered in 1890 by Dutch biologist Beyerinck who made the first experimental seaweed culture. Its wealth of nutrients (protein, vitamins, minerals, amino acids and chlorophyll) and its ability to multiply rapidly aroused the interest of scientists and policy. During the First World War, a German microbiologist, Hardner Lindner, conducted an experiment to feed German troops with chlorella. In the aftermath of the Second World, the governments of industrialized countries believe that chlorella could be a «super food ” of high nutritional value (400 kcal per 100 g for Chlorella vulgaris) can eliminate hunger in the world. In 1948 the Stanford Research Institute (USA) showed that Chlorella could be grown and harvested in large quantities. However, researchers have found that it was relatively difficult to grow and she lost most of its nutritional value when processed.
Chlorella contains substantial amounts of lipid (particularly polyunsaturated fatty acids), proteins, chlorophyll, carotenoids, vitamins (B12 and K vitamins, minerals and special pigments.
Fibromyalgia: A case study was conducted with derivatives supplements the unicellular green alga Chlorella, 20 patients with moderate to severe symptoms of fibromyalgia. Participants consumed during two months 10g tablets Chlorella and 100mL of chlorella extract. Based on interviews and questionnaires, self-evaluation, seven patients reported that chlorella reduced fibromyalgia symptoms, while six said they had experienced no change, and five reported that their symptoms had worsened. Another trial also reported encouraging results. However, more rigorous studies are needed to confirm these results.
Hypertension: Two clinical studies have shown that chlorella (10g per day for 2 to 3 months in capsule form) slightly decreases blood pressure. This decrease comes in one of two studies to lower cholesterol levels. In the second study, 24 hypertensive patients were treated for two months 10g chlorella tablets in 100mL Wakasa Gold. The effect was accompanied by a slight drop in blood pressure. The authors also noted that patients treated with extract pointed out that their health had improved.
Skin cancer: Several studies in mice have reported that Chlorella vulgaris inhibits proliferation of cancer cells. However, only one study has been conducted to date on patients with cancer of the skin, and the results are inconclusive.
Ulcerative colitis: A randomized controlled trial indicates that chlorella can reduce ulceration associated colitis. Although the results are promising, more rigorous studies are needed to confirm or refute these results.
Adjuvant vaccine: Chlorella has shown some activity in modulating the immune system. However, these properties obtained in vitro were not confirmed in humans. Indeed, a controlled, randomized, double-blind evaluated the effect of oral supplementation of Chlorella (200 or 400 mg for 28 days) on the immune response of 124 adults aged 50 years and older. 21me to date, the authors received a single dose of a vaccine against influenza. It appears that the chlorella does not increase the production of antibodies, compared with the control group.
Detoxification: A clinical study emphasizes that Japanese speakers who consumed Chlorella pyrenoidosa supplementation have subsequently fewer toxins in their breast milk than control subjects not having consumed.
Precautions / Contraindications / Side Effects:
In general , it is difficult to evaluate the optimal dose of the natural extracts in which the above side effects counteract their effectiveness . On chlorella, the short-term supplementation is safe, contrary to long-term consumption.
Chlorella is cons -indicated in individuals with allergies to chlorella, its ingredients or family (Oocystaceae). It is also cons -indicated in children susceptible to mold.
Other side effects include sensitivity to light, asthma, fatigue and skin problems.
Chlorella should be used with caution in individuals:
- With hypotension or treated with anti –hypertensive.
- Taking drugs that modulate the immune system as chlorella can stimulate the immune system.
- Treated with an anti -cancer drug.
- Sensitive to light.
- Taking supplements of manganese. A clinical study reported a case of parkinsonian disorders and blood levels of manganese which is caused by long-term consumption of chlorella extract containing 1.7 mg of manganese. These symptoms eased later after stopping use.
- Consuming vitamin K in the form of supplements or foods because chlorella contains large quantities.
Chlorella can interact with the following drugs or supplements :
- Anticoagulants and antiplatelet.
- Chlorella contains significant quantities of potassium which can interact with Warfarin for example.
- Anti -inflammatory.
- Detoxifying agents.
- Blockers heavy metals (chlorella may increase the urinary excretion of heavy metal cadmium).
- Immunosuppressant .
- Vaccines: Vaccine ONC- 107 (Respondin ®) derived from an extract of Chlorella pyrenoidosa could stimulate the antibody response to influenza vaccine.